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One understands by histamine intolerance or even Histaminose the quarrelsomeness of the histamine taken up with the food whose cause a lack the histamine shows to diminishing enzymes Diaminoxidase (DAO) or Histamin-N-Methyltransferase (HNMT) or a disproportion between supply and dismantling of the histamine. This particular theory was developed in the Eighties within the scope of the investigation of the biogenic amine. In the opinion associated with some authors the histamine intolerance isnt innate, but an acquired clinical picture by which simply 1% of the European population would be concerned. 80% of the ill individuals are of female gender associated with middle age. The illness symptoms can disappear in the pregnancy, nevertheless, appear after the pregnancy again.
Controlled single research and a comprehensive Metaanalyse from 2003 could find up to now no scientific proofs of the postulated food intolerance through biogenic amine like the histamine. The histamine intolerance is neither an allergy nor a not really immunologische food quarrelsomeness separate a taking apart disturbance. She is possibly an effect or companion of additional quarrelsomeness or allergies. For the prognosis an anamnesis is important. Because, however, a lot of discomfort can have for example headaches, migraine, bronchial asthma bronchial, Hypotonie, heart rhythm disturbances as well as Dysmenorrh? also other causes than the usual histamine intolerance, it does not surprise that 1 / 2 of the suspicion diagnoses are wrong. The diagnosis is usually produced by a provocation. Because, however, histamine can release potentially life-menacing states, the following process manner is recommended: Pre and post a 14-day diet blood is actually taken to the regulation of the actual histamine and Diaminoxydasespiegels and is compared. Instead of supplying histamine, histamine is taken away by the diet. This process manner does not endanger the patient, on the contrary: By presentation of a histamine intolerance the discomfort is improved or completely disappeared. At the same time the histamine mirror and the DAO sections itself rises (both significantly. If no histamine intolerance is given, the actual blood values and also not really the discomfort do not alter. At the same time must be excluded a food allergy, cross reactions with pollen, a Fruktosemalabsorption, a lactose intolerance and a Z?liakie. The basis of the treatment exists in a reduction of the histamine provided with the food by observance of a diet plan free of histamine. A maximum variance is from the dermatologists because decades with the Urticaria successfully used "potato rice diet", so one week only potatoes, rice, salt, sugar as well as water. Moreover, should be avoided in the opinion of the therapists Nahrungsmittel who do not contain a lot of histamine although themselves, but in the body ought to release stored histamine, wennn a histamine intolerance is given.